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. 2011 Jul 22;17(11-12):1204–1212. doi: 10.2119/molmed.2011.00063

Figure 5.

Figure 5

Changes in renal cortical immunolocalization of collagen type I and type IV and collagen levels in WT and TRPV1−/− mice after 4 wks of deoxycorticosterone acetate (DOCA)-salt treatment. (A, B) Representative immunostained kidney sections showing the immunostaining of collagen type I and type IV (in red) in control WT and TRPV1−/− mice (a and b), and WT and TRPV1−/− mice (c and d) treated with DOCA-salt. Arrows point to collagen type I-positive staining (A) or collagen type IV-positive staining (B). Magnification, 400×. (C) Bar graph shows the changes in renal collagen levels in WT and TRPV1−/− mice with or without DOCA-salt treatment. Values are mean ± SE (n = 7 to 8). *P < 0.05 compared to control WT or TRPV1−/− mice; †P < 0.05 compared to DOCA-WT mice.