Table 1.
Subject characteristics.
ST (n = 6) (disease duration <2 years) | LT (n = 7) (disease duration >10 years) | P | |
---|---|---|---|
Disease duration (years) | 0.79 ± 0.49 | 15.29 ± 5.53 | 0.003a |
Age | |||
Mean | 25.7 ± 2.66 | 43.1 ± 9.16 | 0.008a |
Median | 25.5 | 45 | |
Range | 23–29 | 27–55 | |
Sex | |||
Female (%) | 83 | 100 | |
Male (%) | 17 | 0 | |
Ethnicity | |||
African American (%) | 17 | 57 | 0.242 |
Hispanic (%) | 83 | 29 | 0.103 |
Caucasian (%) | 0 | 14 | 0.462 |
Education (years) | 12.83 ± 2.14 | 12.85 ± 3.02 | 0.942 |
SLEDAI | 1.67 ± 1.5 | 2.0 ± 2.30 | 0.940 |
DI | 0.17 ± 0.41 | 1.29 ± 1.25 | 0.048a |
History of NPSLE | 0 | 0 | |
Anti-dsDNA titer (%)b | 33 | 43 | 0.59 |
Anticardiolipin (%)c | 33 | 29 | 0.72 |
Prednisoned | 14.17 ± 14.71 | 4.11 ± 5.62 | 0.127 |
Cellcept(current) | 67% | 14% | 0.063 |
Azathioprine(current) | 0 | 14% | 0.355 |
Cyclophosphamide(current) | 17% | 0 | 0.280 |
Current DMARDe | 83% | 29% | 0.058 |
DMARD ever | 83% | 71% | 0.626 |
Hypertensionf | 50% | 0 | 0.181 |
Diabetes mellitusg | 0 | 14% | 0.355 |
P < 0.05.
Current anti-dsDNA titer; percent positive.
Anticardiolipin antibody titer; percent positive IgG or IgM by history.
Current prednisone dose.
DMARD, disease-modifying antirheumatic drugs include cyclophosphamide, methotrexate, azathioprine or cellcept for >2 months.
Current hypertension requiring medication.
Current diabetes mellitus requiring medication.