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Survival
| E10.5 | E11.5 | E13.5 | P21 | |
|---|---|---|---|---|
| Total embryos | 227 | 40 | 18 | 151 |
| Dot1L+/+ (WT) | 61 (27%) | 14 (35%) | 4 (22%) | 53 (35%) |
| Dot1L+/− (Het) | 114 (50%) | 19 (48%) | 12 (67%) | 98 (65%) |
| Dot1L−/− (KO) | 52 (23%) | 7 (18%) | 0 (2)* (11%) | 0 (0%) |
Embryos were dead but not resorbed.
