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. 2012 Mar 21;32(12):4042–4048. doi: 10.1523/JNEUROSCI.6032-11.2012

Figure 3.

Figure 3.

Light-evoked IPSCs and EPSCs are inhibited by opioid receptor activation. A, Plot of light-evoked IPSC amplitudes over time shows an inhibition of light-evoked IPSCs by the nonspecific opioid agonist ME (10 μm). The IPSC inhibition is reversed by application of the MOR-selective antagonist CTAP (500 nm). B, Representative traces of IPSCs in control conditions and in the presence of ME. C, ME inhibits light-evoked EPSC amplitude and EPSC amplitude returns to baseline upon washout of ME. D, Representative traces of EPSCs in control conditions and in the presence of ME. The arrowheads in B and D indicate the timing of the light pulse.