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. 2012 Jan 4;119(13):3105–3112. doi: 10.1182/blood-2011-09-380840

Figure 2.

Figure 2

The magnitude of HIV-1 Gag-specific T cells does not differ significantly between IRIS and non-IRIS patients. The total response magnitude, measured by production of IFN-γ and/or IL-2 and/or TNF, generated by HIV-1 Gag reactive CD4+ (A) and CD8+ T cells (B) of IRIS and non-IRIS patients were compared at the 5 analysis time points. Graphs represent interquartile ranges, median bars, as well as individual data points. Dashed lines separate pre-ART from on-ART samples. Gray boxes indicate samples from IRIS patients within 3 months of clinical IRIS onset. All time points were compared between patient groups (no statistically significant differences found) and to corresponding pre-ART measurements within each patient group: red asterisks for IRIS; and blue asterisks, non-IRIS (indicated below graphs). *P < .01; **P < .001.