Table. Epidemiologic and microbiologic characteristics for Panton-Valentine leukocidin–positive MRSA infections in 9 case-patients, Shanghai, People’s Republic of China, 2006*.
| Strain | Age/sex | Admission month | Onset | Diagnosis† | Resistance pattern‡ | Resistance determinants§ | ST§ | SCCmec | spa type | PFGE |
|---|---|---|---|---|---|---|---|---|---|---|
| D8 | 1 mo/F | Feb | HA | Pneumonia | Chl, Ery, Gen, Mup | aacA-aphD, ermC, ileS-2 | ST30 | IV | t318 | SH100 |
| D9 | 1 mo/F | Feb | CA | Pneumonia | Gen, Mup | aacA-aphD, ileS-2 | – | IV | t318 | SH100 |
| D13 | 1 mo/M | Mar | HA | Pneumonia | Gen | aacA-aphD | – | IV | t318 | SH100 |
| D14 | 3 mo/M | Mar | CA | Pneumonia | Gen | aacA-aphD | – | IV | t318 | SH100 |
| D16 | 1 mo/M | Mar | CA | Pneumonia | Gen, Mup | aacA-aphD, ileS-2 | – | IV | t318 | SH100 |
| D12 | 3 mo/F | Mar | HA | Pneumonia | Ery | ermC | ST1114 | V | t318 | SH100 |
| A18 | 29 y/M | Mar | HA | Prostatitis | None | – | ST30 | IV | t3384 | Singleton |
| D7 | 1 mo/F | Jan | CA | Pneumonia | Ery, Gen | aacA-aphD, ermC | ST88 | V | t1376 | SH200 |
| D18 | 4 mo/M | Apr | CA | Pneumonia | Ery, Gen | aacA-aphD, ermC | – | V | t1376 | SH200 |
*Strains are designated by hospital code and strain number. MRSA, methicillin-resistant Staphylococcus aureus; ST, sequence type; SCC, staphylococcal cassette chromosome; spa, staphylococcal protein A; PFGE, pulsed-field gel electrophoresis; HA, healthcare-associated; Chl, chloramphenicol; Ery, erythromycin; Gen, gentamicin, Mup, mupirocin; acA-aphD, aminoglycoside resistance gene encoding the bifunctional enzyme, 6'-aminoglycoside N-acetyltransferase/2”-aminoglycoside phosphotransferase; ermC, gene encoding macrolide-lincosamide-streptogramin B resistance; ileS-2, gene encoding high-level mupirocin resistance mediated by isoleucyl tRNA-synthetase; CA, community-associated. †According to the diagnosis given in the computerized record. In the 8 children, MRSA was isolated from sputum specimens. One child also had MRSA isolated from pleural fluid. Because limited information was provided in the computerized records, some of the isolations may represent respiratory colonization. The outcomes of the 8 children were unknown. ‡According to disk diffusion test (1,5). §Determined by PCR as described (4,6). ST30 (allelic profile 2–2-2–2-6–3-2) and ST114 (139–2-2–2-6–139–2) belonged to clonal complex 30.