Table. Demographic and clinical characteristics of febrile patients with Bartonella infection compared with febrile patients who had no evidence of Bartonella infection, Thailand, 2002–2003*.
Variables | No. (%) Bartonella-infected case-patients,† n = 57 | No. (%) non–case-patients,‡ n = 193 | p value |
---|---|---|---|
Median age, y (range) | 19 (7–72) | 20 (7–79) | 0.9 |
Male sex |
37 (64.9) |
113 (58.5) |
0.4 |
Occupation | |||
Student | 27 (47.4) | 84 (43.5) | 0.6 |
Rice farmer | 20 (35.1) | 40 (20.7) | 0.03 |
Business | 3 (5.3) | 13 (6.7) | 0.7 |
Other§ |
7 (12.3) |
56 (29.0) |
0.01 |
Signs and symptoms | |||
Headache | 44 (77.2) | 161 (83.4) | 0.3 |
Eye pain | 17 (29.8) | 58 (30.1) | 1.0 |
Myalgias | 47 (82.5) | 141 (73.1) | 0.1 |
Extremity pain | 39 (68.4) | 115 (59.6) | 0.2 |
Joint pain | 26 (45.6) | 74 (38.3) | 0.3 |
Vomiting | 22 (38.6) | 80 (41.5) | 0.7 |
Abdominal pain | 12 (21.1) | 64 (33.2) | 0.08 |
Rash | 7 (12.3) | 17 (8.8) | 0.6 |
Lymphadenopathy |
9 (15.8) |
24 (12.4) |
0.5 |
Laboratory results | |||
Anemia (Hb <13 mg/dL) | 30 (60.0) | 93 (50.3) | 0.2 |
Thrombocyte count <100,000/mm3 | 5 (8.9) | 14 (7.4) | 0.7 |
Leukopenia (leukocytes <5,000/mm3) | 10 (17.5) | 63 (32.6) | 0.03 |
Leukocytosis (leukocytes >11,000/mm3) | 20 (35.1) | 33 (17.1) | <0.01 |
Creatinine >1.5 mg/dL | 5 (8.9) | 12 (6.2) | 0.5 |
Bilirubin >1.3 mg/dL | 6 (10.7) | 19 (9.8) | 0.8 |
Alkaline phosphatase >121 IU/L | 36 (64.3) | 132 (68.8) | 0.5 |
AST >36 IU/dL | 18 (32.1) | 88 (45.6) | 0.07 |
ALT >36 IU/dL | 9 (16.1) | 50 (25.9) | 0.1 |
*Hb, hemoglobin; AST, aspartate aminotransferase; ALT, alanine aminotransferase. †Excluded Bartonella-infected patients with serologic evidence of infection with other common pathogens (dengue virus, Leptospira, or Burkholderia pseudomallei; n = 35). ‡Febrile patients with acute-phase and convalescent-phase immunoglobulin G titer against Bartonella species <128. §Other occupation includes housewife, government officer, day laborer, or construction worker.