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. Author manuscript; available in PMC: 2012 Apr 9.
Published in final edited form as: Biol Blood Marrow Transplant. 2008 Sep;14(9):993–1003. doi: 10.1016/j.bbmt.2008.06.009

Table 3.

Multivariate analysis comparing transplant outcomes between HLA-identical patients who received Fludarabine + Busulfan + Thymoglobulin as conditioning (Cases) with HLA-identical patients who received Busulfan + Cyclophosphamide for their conditioning (Controls), after transplantation.

Outcome of interest N eval Relative Risk
(95% Confidence Interval)
P - value
Acute GVHDb
Main effect:
    Controls 215 1.00a
    Cases 120 0.36 (0.21–0.63) 0.0003
Chronic GVHDb
Main effect:
    Controls 213 1.00a
    Cases 120 1.28 (0.83–1.98) 0.2607
Treatment related mortalityb
Main effect:
    Controls 215 1.00a
    Cases 120 0.322 (0.16 – 0.64) 0.0013
Relapse/progressionb
Main effect:
    Controls 215 1.00a
    Cases 120 1.91 (1.14–3.19) 0.0138
Treatment failureb
Main effect:
    Controls 215 1.00a
    Cases 120 0.90 (0.62 – 1.31) 0.5901
Overall survivalb
Main effect:
    Controls 215 1.00a
    Cases 120 0.644 (0.43–0.96) 0.0298

Abbreviations: GVHD= graft-versus-host disease.

a

Reference group.

b

No other covariates were significant.