Sample DXA images. Bone density, mass, and area are calculated for each region of interest (defined by semi-automatic line placement) and the total region of interest in scans of the whole body (A), distal forearm (B), lumbar spine (C), and proximal femur (D). Measures of vertebral heights and type and severity of vertebral deformity are derived from semi-automated marker placement on Vertebral Fracture Assessment images of L4 to T4 (E). (All images were acquired using the Hologic Discovery A scanner, except the forearm scan, which was acquired using the Hologic QDR 4500A.)