Table 2. Immune responses against Plasmodium falciparum and P. vivax in study participants, by village, Somalia, 2008*.
| Characteristic | Village† |
p value‡ | ||
|---|---|---|---|---|
| Xuunshaley | Badahabo | Ceel-Bardaale | ||
| No. persons | 271 | 160 | 697 | |
| Median age, y (IQR) |
20 (7–40) |
17.5 (5–35) |
13 (6–35) |
0.04 |
| P. falciparum immune response | ||||
| Combined | 9.4 (23/244) | 21.7 (30/138) | 20.4 (126/619) | <0.001 |
| MSP-1 | 5.1 (13/254) | 13.4 (19/142) | 15.0 (95/634) | <0.001 |
| 251.2 (155.0–285.3) | 214.8 (169.8–275.5) | 248.5 (190.5–397.2) | 0.12 | |
|---|---|---|---|---|
| AMA-1 | 4.8 (12/252) | 9.2 (13/141) | 8.9 (58/653) | 0.02 |
| 169.1 (137.0–190.9) | 189.3 (158.4–225.5) | 233.7 (170.7–487.0) | 0.12 | |
|---|---|---|---|---|
| P. vivax immune response | ||||
| Combined | 16.1 (40/248) | 21.0 (31/148) | 20.2 (131/648) | 0.33 |
| MSP-1 | 11.9 (30/252) | 13.9 (21/151) | 10.4 (58/648) | 0.33 |
| 333.9 (271.4–463.9) | 342.4 (280.1–374.8) | 291.5 (248.7–393.3) | 0.39 | |
|---|---|---|---|---|
| AMA-1 | 5.2 (13/252) | 7.4 (11/149) | 12.8 (85/665) | 0.001 |
| 151.5 (146.0–202.1) | 183.5 (155.7–275.7) | 227.1 (184.6–390.8) | 0.10 |
*IQR, interquartile range (25th–75th percentile); MSP-1, merozoite surface protein 1; AMA-1, apical membrane antigen 1. †Values are % prevalence (no. positive/no. tested) or approximate median titer (IQR) only for seropositive persons unless otherwise indicated. ‡Adjusted for age and correlations between observations from the same household, when applicable.