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. 2011 Sep;17(9):1692–1700. doi: 10.3201/eid1709.101667

Table A1. Antimicrobial drug susceptibility profiles of CV isolates compared with Mycobacterium chelonae, M. massiliense, and M. abscessus isolates*.

Antimicrobial drug
M. abscessus, n = 41

M. massiliense, n = 5

M. chelonae, n = 58

CV, n = 25
Range
S, %
I, %
R, %
Range
S, %
I, %
R, %
Range
S, %
I , %
R, %
Range
S, %
I, %
R, %
Amikacin 8−32 73.2 26.8 0.0 8−32 60.0 40.0 0.0 8−>256 32.8 51.7 15.5 8−32 92.0 8.0 0.0
Cefoxitin 16−64 9.8 90.2 0.0 16−32 40.0 60.0 0.0 64−> 512 0.0 1.7 98.3 16−64 12.0 88.0 0.0
Ciprofloxacin† <0.25−>32 2.4 0.0 97.6 4−16 0.0 0.0 100.0 1−>32 8.6 17.2 74.2 <0.25−8 60.0 20.0 20.0
Clarithromycin <0.12−4 97.6 2.4 0.0 <0.12 100.0 0.0 0.0 <0.12−>64 98.3 0.0 2.4 <0.12−1 100.0 0.0 0.0
Gatifloxacin‡ <0.5−>16 2.4 14.6 83.0 4−16 0.0 20.0 80.0 1−>16 31.0 44.8 24.2 <0.5−4§ 80.0 20.0 0.0
Imipenem 1−32 14.6 53.6 31.8 8 0.0 100.0 0.0 <0.5−64 10.3 34.5 55.2 1−64 16.0 44.0 40.0
Linezolid 4−32 43.9 36.6 19.5 8−16 20.0 60.0 20.0 <0.1−32 81.0 13.8 5.2 1−32 72.0 24.0 4.0
Minocycline 8−64 0.0 4.9 95.1 64 0.0 0.0 100.0 <0.5−>64 15.5 3.5 81.0 <0.5−16¶ 90.9 9.1 0.0
Tobramycin 4−32 2.4 22.0 75.6 8−32 0.0 0.0 100.0 1−>128 98.3 0.0 1.7 4−16# 62.5 29.2 8.3
Trimethoprim/ sulfamethoxazole 4/76−>16/304 0.0 100.0 >16/304 0.0 100.0 <0.5/9.5−>16/304 5.2 94.8 1/9−>16/304 8.0 92.0

*CV, M. chelonae variant; S, susceptible; I, intermediate; R, resistant; –, not applicable. One CV isolate did not grow on solid media.
†Read at 3 days
‡No CLSI breakpoint recommendation has been proposed for gatifloxacin. Manufacturer recommendation of 4 used as the intermediate breakpoint.
§10 isolates tested.
¶22 isolates tested.
#24 isolates tested.