Figure 2.
Antibiofilm agents inhibition of biomass of Nocardia nova complex biofilms. N. nova complex biofilms were grown for 24 h on silicone disks, placed in 24-well tissue culture plates, and exposed to trimethoprim/sulfamethoxazole (Bacterim) and heparin; trimethoprim, EDTA, and ethanol (EtOH); minocycline, EDTA, and ethanol; or Mueller-Hinton broth medium (control) for 2 h. Minocycline and trimethoprim-based lock solutions completely inhibited the N. nova complex biofilm biomass compared with controls (p = 0.003).