Table. Characteristics of infection in children with Escherichia coli O157 versus E. coli O26, Scotland, 2010*.
| Variable | O157 HUS, n = 12 | O26 HUS, n = 3 | p value |
|---|---|---|---|
| Age, y |
4.5 ± 1.0 |
3.7 ± 1.3 |
|
| Clinical signs and symptoms | |||
| Diarrhea | 12 | 3 | |
| Bloody diarrhea | 8 (67) | 2 (67) | NS |
| Abdominal pain | 8 (67) | 3 (75) | NS |
| Fever | 2 (17) | 1 (33) | NS |
| Neurologic involvement | 3 (25) | 3 (100) | 0.02 |
| Diabetes | 1 (12) | 2 (67) | 0.02 |
| Cardiomyopathy | 0 | 1 (33) | 0.04 |
| Anuria, d |
7.7 ± 2.4 |
15.7 ± 1.3 |
0.04 |
| Clinical parameters | |||
| Leukocyte count × 109/L | 42.1 ± 14.4 | 25.9 ± 4.8 | NS |
| C-reactive protein, mg/L | 93.5 ± 28.4 | 151 ± 74 | NS |
| Serum albumin, g/L | 22.5 ± 1.3 | 22.3 ± 2.4 | NS |
| Lactate dehydrogenase, IU/L |
2,521 ± 362 |
1,991 ± 642 |
NS |
| Admission to ITU | 3 (25) | 3 (100) | 0.04 |
| Duration of hospitalization, d |
13.2 ± 2.2 |
25 ± 3.8 |
0.03 |
| Treatment | |||
| Peritoneal dialysis, d | 7.4 ± 1.9 | 10 | NS |
| Hemodialysis, d | 8.5 ± 1.5 | 8.3 ± 3.0 | NS |
| Hemofiltration | 0 | 3 (100) | 0.001 |
| Laparotomy |
0 |
1 (33) |
0.04 |
| Postdischarge hypertension | 0 | 2 (67) | 0.01 |
*Values are mean ± SE or no. (%). Significance relates to difference between groups. HUS, hemolytic uremic syndrome; NS, not significant, ITU, intensive treatment unit.