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. 2012 Apr 9;7(4):e33619. doi: 10.1371/journal.pone.0033619

Table 1. Significance levels (p values) for gene regions with p≤0.005, for either an association with (i) cervical precancer/cancer, (ii) progression to cervical precancer/cancer, (iii) HPV persistence.

Chromosome # SNPs (i) (ii) (iii)
Gene CIN3+ (n=415) CIN3+ (n=415) HPV persistence (n=356)
vs. RC (n=425) vs. HPV persistence (n=356) vs. RC (n=425)
PRDX3 * 10q25-q26 11 0.00015 0.0744 0.16314
RPS19 * 19q13.2 4 0.00045 0.00585 0.45823
DDX1 2p24 13 0.0006 0.69087 0.21284
TELO2 16p13.3 20 0.0009 0.17849 0.65932
C1RL 12p13.31 20 0.00165 0.14029 0.00875
ILDR1 3q13.33 11 0.00285 0.05830 0.88461
THRAP4 6 0.00370 0.80776 0.05615
GDF10 10q11.22 20 0.00400 0.13639 0.04230
GDF2 10q11.22 19 0.00400 0.12639 0.04080
TYMS 18p11.32 20 0.0055 0.30233 0.0015
EVPL 17q25 10 0.02055 0.08985 0.00180
GC 4q12-q13 19 0.0343 0.0004 0.00965
IL2RA 10p15-p14 44 0.24394 0.00115 0.44318
PIK3CA 3q26.3 11 0.91060 0.05145 0.00490
*

FDR for both PRDX3 and RPS19=0.19.

RC=random controls.