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. 2012 Apr 9;7(4):e31448. doi: 10.1371/journal.pone.0031448

Figure 3. Analysis of conservation of different domains, motifs and interacting sites in TRPV1.

Figure 3

The lower value indicates more conservation and higher value indicates less conservation. Different regions of the TRPV1 are indicated by different colors. Ank: Ankyrin repeat region, TM: Transmembrane region, L: Loop region, CBD: Cholesterol-binding domain, P-loop; Pore loop, TRP-box: Signature motif for TRP box, TBS-1: Tubulin binding sequence 1, TBS-2: Tubulin binding sequence 2, TAD-1: Tetrameric assembly domain 1, TAD-2: Tetrameric assembly domain 2, Cam: Calmodulin binding region, NT: N-terminal cytoplasmic domain of TRPV1, MID: Middle portion of TRPV1, CT: C-terminus of TRPV1, FL: Full length TRPV1, Histone 4: Histone 4. All values are significant (P<0.0001, Kuskal-Wallis test).