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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Dev Biol. 2012 Feb 25;365(1):219–228. doi: 10.1016/j.ydbio.2012.02.027

Figure 5. The ACBD3 binding region of Numb specifically mediates the inhibition of Notch signaling in larval neuroblasts.

Figure 5

(A) Quantification of type II neuroblasts per brain lobe is shown for Wor-GAL4 driving expression of NumbΔAB, NumbS2A, or NumbS2D. (n = 5 per genotype) (B–F) Compared to wild-type flies, overexpression of NumbΔAB, NumbS2A, NumbS2D, or NumbΔC driven by Sca-GAL4 leads to a loss of scutellar bristles. (n = 259, 187, 83, and 34, respectively) (G) Quantification of the number of bristles per scutellum is shown for Sca-GAL4 driving expression of NumbΔAB, NumbS2A, or NumbS2D.