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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Trends Cell Biol. 2011 Dec 21;22(4):177–184. doi: 10.1016/j.tcb.2011.11.005

Figure 2. SAGA is recruited through multiple interactions.

Figure 2

Multiple SAGA subunits interact with both protein factors and chromatin marks that are present at gene promoters in S. cerevisiae. (A) Tra1 interacts with transcription activators. (B) Spt3 and Spt8 interact with TBP and could potentially recruit SAGA to genes containing the core transcription machinery. (C) The bromodomains of Gcn5 and Spt7 interact with acetylated nucleosomes. (D) Sgf73 binds H2A-H2B dimers via a novel Zn-binding motif in its SCA7 domain. (E) Sgf29 binds H3K4me2/3. Adapted from [69].