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. Author manuscript; available in PMC: 2013 Apr 10.
Published in final edited form as: J Control Release. 2012 Jan 15;159(1):104–110. doi: 10.1016/j.jconrel.2012.01.007

Figure 1. Formulation of PBAE polymers and the PBAE polymer-plasmid nanocomplex.

Figure 1

A, The PBAE polymers were synthesized by a simple chemical reaction of 5-amino-1- pentanol and 1,4-butanediol diacrylate monomers at 95° C for 24 hr[30]. B, The synthesized PBAE polymers were fractioned into < 7 kDa and > 7 kDa polymers by dialysis using a 7 kDa MW cut-off membrane. C, The fractioned PBAE polymers were incorporated with the plasmid pMax-GFP (~3.5 kbp) containing a GFP reporter gene to formulate a PBAE polymer-plasmid nanocomplex.