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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Pharmacol Toxicol Methods. 2012 Feb 26;65(2):64–74. doi: 10.1016/j.vascn.2012.02.002

Fig. 3.

Fig. 3

Representative IC50 plots derived from Fl-t-pgp assays. Individual points represent the activity of Pgp in the presence and absence of test compound, normalized to a value of 1 for controls. IC50 values were calculated by fitting the relative activity at each test compound concentration to a monophasic decay. The IC50 value is the test compound concentration causing 50% inhibition of Pgp transport activity.