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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Pharmacol Toxicol Methods. 2012 Feb 26;65(2):64–74. doi: 10.1016/j.vascn.2012.02.002

Fig. 5.

Fig. 5

Representative IC50 plots derived from net transport measurements of [3H]digoxin transport in LLC-MDR1 cell monolayers. Individual points represent the inhibition of Pgp-mediated digoxin transport at varying concentrations of test compounds. IC50 values were calculated by non-linear regression analysis as described in Materials and methods.