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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: J Struct Biol. 2012 Feb 22;178(1):61–73. doi: 10.1016/j.jsb.2012.02.009

Figure 8. Pockets of GAP50 near the homologous active site region in other proteins.

Figure 8

A) Ribbon diagram of PfGAP50 with identified ligands shown in spheres, the orientation is identical to Figure 4A. Pockets and cavities as calculated by PyMol are as light blue surfaces. Pocket 1 (P1) and pocket 2 (P2) are close to the cobalt atom closest to the active site of the human purple acid phosphatase.

B) Electrostatic potential around pockets 1 and 2 in an orientation as viewed in Figure 4B–D, with P2 being more charged compared to P1.