Table 1.
Cytokine/Chemokine Profiles in F344 and HIV-1Tg Rat Serum
| Cytokines and Chemokines in the Serum with LPS Treatment | |||||||
|---|---|---|---|---|---|---|---|
| Protein (pg/ml, ± SD) | |||||||
| F344 | IL-1β | KC/GRO | IL-4 | IL-5 | TNF-α | IFN-γ | IL-13 |
| Interleukin 1 beta | Interleukin 4 | Interleukin 5 | Tumor necrosis factor - alpha | Interferon gamma | Interleukin 13 | ||
| SS+S | 83.0(± 21.3) | 1294.8(± 589.7) | 9.5(± 0.6) | 116.0(± 23.7) | 42.7(± 6.1) | 35.2(± 7.2) | 27.5(± 1.1) |
| SS+L | 272.1(± 145.1) | 7153.2(± 2779.8)** | 15.5(± 1.7)*** | 348.7(± 202.4) | 7531.8(± 7897.0) | 138.6(± 46.2)** | 42.3(± 9.5)** |
| LL+S | 80.4(± 42.4) | 780.9(± 846.6) | 10.3(± 51.2) | 103.6(± 32.6) | 51.2(± 12.4) | 56.5(± 19.6) | 22.5(± 1.1) |
| LL+L | 125.1(± 23.5) | 3293.5(± 680.6)* | 11.1(± 1.1)^^ | 210.0(± 56.7) | 88.2(± 25.5) | 61.8(± 18.9)^^ | 26.5(± 2.1)^ |
| HIV - 1Tg | IL-1β | KC/GRO | IL-4 | IL-5 | TNF-α | IFN-γ | IL-13 |
| Interleukin 1 beta | Interleukin 4 | Interleukin 5 | Tumor necrosis factor - alpha | Interferon gamma | Interleukin 13 | ||
| SS+S | 85.2(± 31.6) | 1907.4(± 978.9) | 10.7(± 2.0) | 154.7(± 83.6) | 45.2(± 11.4) | 67.8(± 32.2) | 26.8(± 0.5) |
| SS+L | 307.4(± 72.9)*** | 7002.2(± 361.0)*** | 14.4(± 2.5) | 258.3(± 37.3) | 2366.7(± 924.4)*** | 122.3(± 13.4)* | 36.2(± 6.6)* |
| LL+S | 47.9(± 7.4) | 327.6(± 110.5) | 8.0(± 1.4) | 29.7(± 34.3) | 42.8(± 7.0) | 18.3(± 24.9) | 22.3(± 1.1) |
| LL+L | 128.6(± 3.0)^^^ | 3051.3(± 1215.7)^^^ | 11.3(± 0.8)^^ | 189.1(± 121.1) | 113.4(± 51.8)^^^ | 71.1(± 9.1)^ | 27.9(± 4.2)^ |
* P < 0.05, ** P < 0.01, *** P < 0.001 greater than SS+S control; ^ P < 0.05, ^^ P < 0.01, ^^^ P < 0.001 less than SS+L; statistically significant changes are bolded