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. Author manuscript; available in PMC: 2012 Apr 10.
Published in final edited form as: Nat Genet. 2011 Jun 12;43(7):712–714. doi: 10.1038/ng.862

Figure 2. Comparison of mutation rate estimates.

Figure 2

Mutation rates estimated from previous studies are shown above the dashed green line. Solid lines encompassing point estimates represent 95% confidence intervals. Dashed lines encompassing point estimates represent reported plausible ranges. ‘Disease-gene Sex-averaged’ rate comes from 13, with 95% confidence intervals calculated as 1.96 times the standard error. ‘Species-divergence Sex averaged rate’ comes from 14, which specifies the plausible range shown here. Species-divergence sex-specific rates come from scaling the sex-averaged point estimate and upper and lower bounds by the ratio of male/female mutation rate of 6.11 estimated by 3. ‘Family Genome-wide Sex-average’ comes from 7, ‘Families Sex-average’ comes from 4.