Table 3.
NO Metabolites in control subjects and sepsis patients
| NO Metabolitea | Controls (n=52) | Sepsis (n=87) | p valueb |
|---|---|---|---|
| Arterial plasma nitrite | 106 (83 - 134) | 106 (85 - 132) | 0.99 |
| Venous plasma nitrite | 67 (55 - 83) | 66 (54 - 81) | 0.90 |
| p valuec | <0.001 | <0.001 | |
|
| |||
| Arterial WB nitrite | 208 (185 - 235) | 237 (212 - 265) | 0.12 |
| Venous WB nitrite | 139 (122 - 161) | 206 (184 - 232) | <0.001 |
| p valuec | <0.001 | <0.001 | |
|
| |||
| Arterial RBC nitrite | 300 (246 - 365) | 374 (282 - 496) | 0.20 |
| Venous RBC nitrite | 165 (109 - 250) | 355 (250 - 504) | 0.006 |
| p valuec | 0.002 | 0.79 | |
|
| |||
| Arterial SNOHb | 45 (32 - 64) | 56 (42 - 76) | 0.31 |
| Venous SNOHb | 123 (96 - 157) | 80 (59 - 110) | 0.03 |
| p valuec | <0.001 | 0.06 | |
|
| |||
| Arterial RBC XNO | 22 (15 - 32) | 19 (13 - 26) | 0.49 |
| Venous RBC XNO | 28 (18 - 45) | 33 (24 - 44) | 0.71 |
| p valuec | 0.27 | <0.001 | |
|
| |||
| Arterial nitrate | 31 (24 - 38) | 43 (34 - 53) | 0.03 |
| Venous nitrate | 24 (19 - 30) | 43 (34 - 52) | <0.001 |
| p valuec | 0.08 | 1.0 | |
a
All metabolite concentrations are nM, except nitrate which is μM.
b
Comparison of concentration in control subjects vs. sepsis patients
c
Comparison of arterial vs. venous concentration