Table 4.
NO metabolites in sepsis survivors and non-survivors
| NO Metabolitea | Survivors (n=59b) | Non-survivors (n=28b) | p valuec |
|---|---|---|---|
| Arterial plasma nitrite | 102 (82 - 127) | 116 (69 - 194) | 0.64 |
| Venous plasma nitrite | 57 (45 - 72) | 91 (61 - 134) | 0.04 |
| p valued | <0.0001 | 0.24 | |
|
| |||
| Arterial WB nitrite | 225 (196 - 258) | 265 (219 - 321) | 0.17 |
| Venous WB nitrite | 197 (171 - 227) | 227 (184 - 279) | 0.26 |
| p valued | 0.0002 | <0.0001 | |
|
| |||
| Arterial RBC nitrite | 420 (321 - 549) | 293 (146 - 588) | 0.33 |
| Venous RBC nitrite | 412 (291 - 582) | 260 (112 - 602) | 0.31 |
| p valued | 0.92 | 0.80 | |
|
| |||
| Arterial SNOHb | 54 (39 - 74) | 65 (33 - 124) | 0.60 |
| Venous SNOHb | 74 (52 - 105) | 94 (49 - 181) | 0.50 |
| p valued | 0.11 | 0.30 | |
|
| |||
| Arterial RBC XNO | 16 (11 - 24) | 24 (13 - 44) | 0.30 |
| Venous RBC XNO | 29 (20 - 42) | 38 (23 - 62) | 0.38 |
| p valued | 0.0016 | 0.16 | |
|
| |||
| Arterial nitrate | 42 (32 - 54) | 45 (29 - 64) | 0.79 |
| Venous nitrate | 39 (30 - 49) | 53 (34 -75) | 0.19 |
| p valued | 0.28 | 0.28 | |
a
All metabolite concentrations are nM, except nitrate which is μM.
b
Two survivors and 1 non-survivor did not have values for WB and RBC nitrite, 2 survivors and 2 non-survivors did not have values for SNOHb and RBC XNO.
c
Comparison of concentration in survivors vs. non-survivors
d
Comparison of arterial vs. venous concentration