Table 2.
Risks and Hazard Ratios of Repeat Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery for Drug-Eluting Stent vs Bare-Metal Stent Eras
| Outcome | No. (%) |
P Value |
Hazard Ratios (95% Confidence Interval) of Drug-Eluting Stent vs Bare-Metal Stent |
||
|---|---|---|---|---|---|
| Bare-Metal Stent Era (n = 38 917) |
Drug-Eluting Stent Era (n = 28 086) |
Crude | Adjusteda | ||
| PCI, mo 3 |
2569 (6.5) | 1939 (6.8) | .05 | 1.06 (1.00-1.13) | 1.06 (1.00-1.13) |
| 6 | 4243 (10.8) | 2753 (9.7) | <.001 | 0.90 (0.86-0.94) | 0.90 (0.86-0.94) |
| 12 | 5917 (15.2) | 3681 (13.1) | <.001 | 0.86 (0.83-0.90) | 0.86 (0.83-0.90) |
| 24 | 7785 (20.0) | 4804 (17.1) | <.001 | 0.85 (0.82-0.88) | 0.85 (0.82-0.88) |
| CABG surgery, mo 3 |
272 (0.7) | 140 (0.5) | <.001 | 0.66 (0.53-0.81) | 0.66 (0.53-0.81) |
| 6 | 740 (1.9) | 281 (1.0) | <.001 | 0.54 (0.47-0.62) | 0.54 (0.47-0.62) |
| 12 | 1129 (2.9) | 478 (1.7) | <.001 | 0.57 (0.51-0.64) | 0.57 (0.51-0.63) |
| 24 | 1635 (4.2) | 759 (2.7) | <.001 | 0.64 (0.58-0.69) | 0.63 (0.58-0.69) |
| PCI or CABG surgery, mo 3 |
2803 (7.0) | 2051 (7.2) | .40 | 1.03 (0.97-1.09) | 1.03 (0.97-1.09) |
| 6 | 4827 (12.3) | 2978 (10.5) | <.001 | 0.85 (0.82-0.90) | 0.85 (0.82-0.89) |
| 12 | 6734 (17.3) | 4046 (14.4) | <.001 | 0.82 (0.79-0.86) | 0.82 (0.79-0.86) |
| 24 | 8875 (22.8) | 5338 (19.0) | <.001 | 0.82 (0.79-0.85) | 0.82 (0.79-0.85) |
Abbreviations: CABG, coronary artrery bypass graft, PCI, percutaneous coronary intervention.
a
Adjusted for age, sex, race, history of myocardial infarction, congestive heart failure, vascular disease, pulmonary disease, dementia, diabetes, liver disease, kidney disease, cancer.