Table 2.

Demographics (Minor Allele Frequency) of Study Subjects

	MAF (95% CI)
	Control	Cases	p-Value
All	44.0 (40.7, 47.3)	44.9 (42.0, 47.8)	0.7165
Female	42.4 (37.7, 47.3)	47.4 (44.1, 50.6)	0.1032
Male	45.2 (40.9, 49.7)	33.5 (27.3, 40.3)	0.0049
Anti-CCP positive
All	44.0 (40.7, 47.3)	46.8 (43.3, 50.3)	0.2555
Female	42.4 (37.7, 47.3)	49.5 (45.7, 53.4)	0.0295
Male	45.2 (40.9, 49.7)	33.1 (25.6, 41.5)	0.0128
Anti-CCP negative
All	44.0 (40.7, 47.3)	42.8 (37.4, 48.4)	0.7384
Female	42.4 (37.7, 47.3)	44.6 (38.5, 50.9)	0.6214
Male	45.2 (40.9, 49.7)	35.9 (25.3, 48.2)	0.1811

MAF, minor allele frequency; CI, confidence interval; CCP, cyclic citrullinated peptide.