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. 2011 Jul 15;10(14):2355–2363. doi: 10.4161/cc.10.14.15948

Figure 2.

Figure 2

Transcription profle of myoblasts exposed to Doxorubicin treatment. Primary Human Skeletal Muscle Myoblasts (HSMBs) were exposed for 18 h to Doxorubicin 0.4 µM while growing in GM and then shifted in DM for additional 24 h. Total RNA was extracted with Trizol® as described in the data sheet (Invitrogen). A microarray was performed using Sentrix Human Ref-8 BeadChip (Illumina). In the panel is shown the analysis of the differentially expressed transcripts divided in upregulated (left) and downregulated (right). Bar charts represent the functional categories statistically more significant (≥ 2-fold change) in our groups of genes that include GO Biological Process, GeneGo Process Network and GeneGo Pathway Maps. Analyzed using MetaCore™ software from GeneGo Inc.