Figure 1.

Different structures of the antral mucosa from mouse, swine, and men. Quantitative evaluation of cell nuclei per field (96 mm²). Cell nuclei were visualized with a DAPI-staining (blue). (A) Exemplary view onto a horizontal section through the antral mucosa of mouse reveals the characteristic, densely arranged annuli. (B) Horizontal tissue section through the porcine antral mucosa clearly indicates that the annuli in the antral mucosa of swine are bigger in size and are arranged in a lower density when compared with the murine antrum (B). (C) The antral mucosa of men comprises loosely arranged annuli which are comparatively large in diameter compared to murine and porcine antral mucosa. (D) DAPI-stained cell nuclei were counted in a field of 96 mm² on three consecutive horizontal sections through the gastric antral mucosa of each species. Whereas the average number of cell nuclei per field in the antrum of mouse is determined as 933.34 ± 26.03 the average numbers for swine (694 ± 8.61) and human (538.34 ± 38.36) are significantly lower. Data are expressed as mean numbers ± SEM. Statistically significant results determined by the unpaired t-test are indicated by **P < 0.001 to 0.01; ***P < 0.001. Scale bars: (A–C) = 50 μm.