Figure 13.

G-cells do not express the effector enzyme PLCβ2. Double-label immunohistochemistry combining antibodies for PLCβ2 (green) and gastrin (red) on horizontal tissue sections through the antrum of mouse (A–C) or the human antrum (D–F). (A,D) PLCβ2-positive cells in the antrum of mouse (A) and men (D). (B,E) G-cells are located in the same antral regions. (C,F) The overlay of accordant images clearly demonstrates that neither murine (C) nor human (F) G-cells coexpress PLCβ2. Sections are counterstained with DAPI (blue). Scale bars: (A–F) = 20 μm.