Fig. 3.

Bioinformatics pipeline used to define the in silico core matrisome. A, List of the 55 InterPro domains used to define the core matrisome. This list was compiled based on prior knowledge, data from the literature and iterative query of UniProt as described in Extended Experimental Procedures (see also supplemental Table S2A). B, Schematic representation of the bioinformatic pipeline (see text, Extended Experimental Procedures and supplemental Fig. S1).