Table 3. Summary of reference-model restraint refinement for related cyclic GMP-dependent kinases originally described in Kim et al. (2011 ▶).

	Validation criteria	cAMP-bound (2.49)	cGMP-bound (3.2)	cGMP-bound with reference (3.2)	Apo (2.75)	Apo with reference (2.75)
All-atom contacts	Clashscore, all atoms	16.53	56.57	25.79	28.52	22.51
	Clashscore percentile	81st	15th	87th	46th	80th
Protein geometry	Poor rotamers (%)	2.61	18.58	4.00	10.53	3.89
	Ramachandran outliers (%)	0.00	2.02	0.40	3.19	0.60
	Ramachandran favored (%)	98.80	85.48	96.40	89.02	96.61
	C deviation > 0.25	0	23	0	3	0
	MolProbity score	2.04	3.84	2.60	3.29	2.51
	MolProbity score percentile	95th	12th	96th	12th	86th
	Residues with bad bonds (%)	0.00	2.38	0.00	0.79	0.00
	Residues with bad angles (%)	0.00	5.95	1.18	0.98	0.39
Residuals	R work	0.1960	0.2102	0.1985	0.2205	0.2167
	R free	0.2264	0.2582	0.2389	0.2612	0.2543