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. Author manuscript; available in PMC: 2012 May 13.
Published in final edited form as: Circ Res. 2011 Mar 31;108(10):1226–1237. doi: 10.1161/CIRCRESAHA.110.239046

Figure 6. ISO injury increases the number of BrdU+ non-myocyte and myocyte nuclei in the ventricle.

Figure 6

Experimental approaches were as described in Figure 6. Representative BrdU+ myocyte and non-myocyte nuclei (at Day 38) are shown in A and B. C: The number of BrdU+ nuclei was greatest during the injury phase (Day 10) and decreased rapidly afterwards. Nuclei labeled during injury (Pulse) were still present 4 weeks later (Day 38; Chase). D: The number of BrdU+ myocytes increased during the first week after injury (Day 17) and returned to control levels by Day 38. BrdU infusion during injury (Pulse), when few Brdu+ myocytes were found, resulted in BrdU labeling of myocyte nuclei at Day 38 (Chase). *P<0.05; **P<0.01; ***P<0.001 versus Control. Data are presented as mean ± SEM.