Fig. 11.
KCNE2 and rapid delayed rectifier K channels (IKr) remodeling during chronic myocardial infarction in canine ventricular myocytes. Chronic myocardial infarction is created by microembolizations as described previously (12). Whole tissue lysates from 4 control and 4 microembolized canine left ventricles are probed with an ERG1a-specific Ab (11) and Ab1 (antibodies listed on the left). The ERG1a-specific Ab recognizes a major 130-kDa dERG1a band, and Ab1 recognizes a major 20-kDa KCNE2 band in canine heart.