Table 2. Acute- and convalescent-phase serologic and microscopy diagnosis of leptospirosis by MAT,a IgM-ELISA, IHA, and IHC assay in California case reportsb.
| Case | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Days post exposure |
9 |
11 |
15 |
32 |
21 |
36 |
23 |
44 |
Acute |
conv |
|
| MAT |
ND |
ND |
Neg |
1:3200 |
Neg |
1:800 |
1:800 |
1:200 |
Neg |
ND |
|
| ELISA |
ND |
ND |
Neg |
Pos |
Pos |
ND |
Pos |
ND |
Pos |
ND |
|
| IHA |
1:50 |
1:800 |
ND |
ND |
ND |
ND |
ND |
ND |
ND |
1:200 |
|
| IHC assay | NA | NA | NA | Pos | Pos | ||||||
aMAT, microagglutination test. Highest MAT titer reported to any leptospira serogroup. bIgM-ELISA, immunoglobulin M–Enzyme-Linked ImmunoSorbent Assay; IHA, indirect hemagluttination assay; IHC, immunohistochemical; NA: not available; ND: not done.