FIGURE 1.

Simplified electron transport chain network together with the considered model variants. The model variants for the single knock-out mutant lines are given in dark blue for d2hgdh-2, green for ivdh-1, and yellow for both etfqo-1 and etfqo-2, resulting in four alternatives. The model variants of the single knock-out mutant lines with exclusion of phytanoyl-CoA are highlighted in light blue followed by x. Analogously, the model variants of the wild type with exclusion of GABA permease are given in red followed by x. A check mark next to an enzyme denotes inclusion of the corresponding reaction in the investigated model variants.