FIGURE 2.

Amino acid sequence alignment of tablysin-15 with taxonomically diverse CAP domain proteins. α-Helical segments are indicated as black arrows, and β-strands are indicated by green lines. The RGD motif is colored in blue. The PROSITE motifs CAP1 and CAP2 are bordered in red. The histidine positions forming the conserved metal-binding site in CAP domain proteins are highlighted in black. Ves V5, Ves v 5, Vespula vulgaris (Insecta); Soli 3, Sol i 3, Solenopsis invicta (Insecta); Na_Asp_2, Na-ASP-2, Necator americanus (Chromadorea); CRIS_CAPVO, CRISP-2, Cavia porcellus (Mammalia); GAPR1_Mus, Golgi-associated plant pathogenesis-related protein 1, Mus musculus (Mammalia).