The histidine decarboxylation pathway is controlled by the pmf. Histamine production by resting cells expressing the HDC pathway. Cells were incubated at an A600 of 1 in 100 mm KPi (A) and 200 mm KPi (B) (pH 5.0) containing 5 mm histidine without further additions (A and B, ●) in the presence of 25 μm CCCP (A, ○; B, ■), 10 mm glucose (A, ▾), and in the presence of 1 μm valinomycin (B, ○), 1 μm nigericin (B, ▾), 1 μm valinomycin, and 1 μm nigericin (B, △).