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. 2012 Jan 12;106(4):733–739. doi: 10.1038/bjc.2011.592

Table 3. Biomarker selection in set 1.

Marker Avg.Imp Rank P-value
EGFR 30.13 1 0.000
ApoA1/proApoA1 29.70 2 0.000
TTR 29.17 3 0.000
proApoA1 26.89 4 0.000
RANTES 26.78 5 0.000
ApoA1 25.35 6 0.000
ApoA2 24.60 7 0.000
DD 24.03 8 0.000
VN 23.61 9 0.000
IL-6 18.71 10 0.000
CRP 18.47 11 0.000
A2M 17.25 12 0.000
PAI-1 16.80 13 0.000
       
ApoC3 16.31 14 0.000
ApoC2 15.24 15 0.000
fPSA 14.08 16 0.118
VDBP 13.24 17 0.000
AFP 12.98 18 0.004
Hp 11.73 19 0.043
sVCAM-1 11.37 20 0.000
DKK3 10.94 21 0.000
ApoA4 9.45 22 0.309
CA19-9 9.13 23 0.525
A1AT 8.99 24 0.349
Hemo 8.96 25 0.663
PSA 8.24 26 0.404
sICAM-1 7.77 27 0.702
fPSA/tPSA 7.16 28 0.875
CA125 6.84 29 0.401
CEA 6.29 30 0.877
B2M 5.79 31 0.962

Abbreviations: AFP=α-fetoprotein; Apo=apolipoprotein; A1AT=α-1-antitrypin; A2M=α-2 macroglobulin; β 2M=β2-microglobulin; CA=cancer antigen; CEA=carcinoembryonic antigen; CRP=C-reactive protein; DD=D-dimer; DKK.3=Dickkopf 3; EGFR=epidermal growth factor receptor; fPSA=free prostate-specific antigen; Hp=Haptoglobin α; IL=interleukin; PAI-1=plasminogen activator inhibitor-1; proApo=pro-apolipoprotein; PSA=prostate-specific antigen; RANTES=regulated upon activation, normally T-expressed and presumably secreted; sICAM=soluble intercellular cell adhesion molecule-1; sVCAM=soluble vascular cell adhesion molecule-1; tPSA=total prostate-specific antigen; TTR=transthyretin; VDBP=vitamin D-binding protein; VN=vitronectin.