Table 1. Baseline patient and tumour characteristics by trial interventions.

	Platinum-based regimen				Number of drugs
	Yes (N=216)		No (N=217)		2-Drugs (N=212)		3-Drugs (N=221)
	No.	%	No.	%	No.	%	No.	%
Median age (range), years	63 (29–79)		64 (35–77)		62.5 (29–77)		64 (41–79)
Gender
Male	170	79	176	81	170	80	176	80
Female	46	21	41	19	42	20	45	20
ECOG PS
0	132	61	132	61	128	60	136	62
1	74	34	77	35	75	35	76	34
2	10	5	8	4	9	4	9	4
Stage
IIIB	46	21	42	19	45	21	43	19
IV	170	79	175	81	167	79	178	81
Method of diagnosis
Histology	145	67	144	66	137	65	152	69
Cytology	62	29	63	29	65	31	60	27
Missing value	9	4	10	5	10	4	9	4
Histology
Adenocarcinoma	90	42	92	42	90	42	92	42
Squamous	59	27	60	28	55	26	64	29
Large cell	6	3	2	1	4	2	4	2
NOS	61	28	63	29	63	30	61	27

Abbreviations: ECOG=Eastern Cooperative Oncology Group; NOS=not otherwise specified; PS=performance status.