Table 2. Relationships between clinic-pathological factors and cancer-specific survival, in patients selected for potentially curative resection for oesophageal adenocarcinoma (n=98).

	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)	P-value	Hazard ratio (95% CI)	P-value
Patient-related factors
Age (<65/65–74/⩾75 years)	1.69 (1.11–2.59)	0.016	1.93 (1.23–3.04)	0.004
Sex (male/female)	0.47 (0.17–1.31)	0.148
mGPS (0/1/2)	2.39 (1.36–4.18)	0.002	2.91 (1.51–5.62)	0.001
Tumour-related factors
TNM stage (I/II/III)	2.27 (1.42–3.64)	0.001		0.345
Tumour differentiation (well-mod/poor)	2.52 (1.43–4.44)	0.001		0.202
Resection margin (R0/R1)	1.80 (0.99–3.29)	0.053		0.805
Positive to total lymph node ratio (0/⩽0.2/>0.2)	2.47 (1.71–3.58)	<0.001	2.38 (1.60–3.52)	<0.001
Neo-adjuvant therapy (no/yes)	1.39 (0.74–2.61)	0.304
Adjuvant therapy (no/yes)	1.74 (0.83–3.65)	0.141
Klintrup–Makinen score (low/high grade)	0.35 (0.15–0.82)	0.016		0.076
Necrosis score (low/high grade)	1.12 (0.64–1.97)	0.695
CD8 tertiles	0.69 (0.48–0.99)	0.048		0.697
CD68 tertiles	1.38 (0.99–1.94)	0.061	1.49 (1.02–2.18)	0.041
Ki67 tertiles	1.46 (1.01–2.12)	0.048		0.479
CD34 tertiles	0.94 (0.67–1.34)	0.736

Abbreviations: CI=confidence interval; LNR=lymph node ratio; mGPS=modified Glasgow Prognostic score; TNM=tumour node metastasis.