Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jan 31;106(4):685–692. doi: 10.1038/bjc.2012.6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2012 Cancer Research UK

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effect of lovastatin and docetaxel on p21 and p27 expression. HGT-1 cells were treated with 12.5 μM lovastatin (L12.5) or with 5 or 10 nM docetaxel (D5 or D10) alone or in combination for 48 h. (A) p21 and p27 mRNA levels were analysed by real-time RT–PCR. Relative mRNA levels were normalised to GAPDH mRNA levels. Values are means±s.d. (n=4). ^*Compared with control, ^#compared with docetaxel treatment, †compared with lovastatin treatment. One symbol: P<0.05, two symbols: P<0.01, three symbols: P<0.001 (Student's t-test). (B) p21 and p27 protein levels were analysed by western blotting. Hsc70 was used as a loading control. The western blotting analyses are representative of three experiments with similar results.