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NOX4 mRNA are increased in adipose tissue from genetically obese mice. ob/ob and db/db mice and C57BL/6 littermates were fed a chow diet for 24 weeks. Epididymal fat was isolated and analyzed by real time RT-PCR using a Nox4-specific primer and probes (A, n = 5; B, n = 8). *, p < 0.001 versus C57BL/6.
