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. 2012 Jan 24;287(13):10525–10534. doi: 10.1074/jbc.M112.340612

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© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 8. — RvE3 formation in vivo. Comparison of endogenously formed 17,18-diHEPEs in mouse inflammatory exudates with enzymatically generated RvE3 isomers. Top panel, MRM chromatogram with established transition of 333/201 m/z to monitor 17,18-diHEPEs present in murine peritoneal exudates 48 h after zymosan challenge. Middle and lower panel, MRM chromatogram obtained from co-injection of enzymatically generated 18S-RvE3 (middle panel) or 18R-RvE3 (lower panel) with 17,18-diHEPEs present in murine peritoneal exudates 48 h after zymosan challenge.