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Molecular models of PAR4. A, structural model of PAR4 based on squid rhodopsin generated with Swiss modeler. TM1 is indicated in red, and TM4 is indicated in blue. Residues that are directed away from the other TM helices are shown as stick diagrams and are labeled using the nomenclature of Ballesteros and Weinstein (33). B, alignment of TM4 sequence from PAR4 and rhodopsin using the alignment program T-coffee.
