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Three-dimensional structures of CNL and dimer-forming interactions. A, structure of the monomer in a tree-like orientation. B, structure of the dimer with bound lactose molecules (blue) and a 2-fold symmetry axis. Interacting β4-β5 loops are indicated by * and β10-β11 loops by §. C, hydrophobic interactions between the two β4-β5 loops. D, interaction between the two β10-β11 loops. Hydrogen bonds are shown as orange dashed lines.
