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. Author manuscript; available in PMC: 2012 Apr 10.
Published in final edited form as: Circulation. 2011 Aug 22;124(12):1382–1390. doi: 10.1161/CIRCULATIONAHA.110.009704

Figure 5.

Figure 5

Effects of probucol on 3H-cholesteryl oleate high-density lipoprotein (3H-CEs-HDL) clearance in ATP-binding cassette transporter 1 (ABCA1) knockout (KO) mice. Mice (n=6 in each group) were fed the experimental diets for 2 weeks, and HDL turnover studies were performed as described in Methods on DBA/J (wild-type [WT]) and ABCA1 KO mice. A, Change in 3H-CEs-HDL in plasma. B, Fractional catabolic rate (FCR) of 3H-CEs-HDL. C, 3H-cholesterol in the liver. D, 3H-sterol in feces. cpm Indicates counts per minute. Significant differences indicated with *P<0.05 (versus control).