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Red arrows show factors that promote mitosis, whereas blue ones support interphase. +PO4 and –PO4 denote phosphorylation and dephosphorylation, respectively. PPase-X and PPase-Y are the as-yet-unidentified protein phosphatases that deactivate the Gwl pathway. ARPP-19, cyclic-AMP-regulated phosphoprotein of 19 kDa; CDK1, cyclin-dependent kinase 1; Ensa, α-endosulfine; Gwl, Greatwall.
