Table 1. Clinical and epidemiologic characteristics of patients harboring clustered versus nonclustered strainsa.
| Parameters | No. (%) of patients in |
|||
|---|---|---|---|---|
| Clustered group | Nonclustered group | OR for clustering (95% CI) | p value | |
| Age, y | ||||
| 15–45 | 63 (81) | 15 (19) | 4.52 (1.6 to 12.96) | 0.001 |
| >46 | 13 (48) | 14 (52) | ||
| Sex | ||||
| Male | 53 (72) | 21 (28) | 0.88 (0.30 to 2.49) | NS |
| Female | 23 (74) | 8 (26) | ||
| HIV status | ||||
| Seropositive | 2 (100) | 0 (0) | UD | |
| Seronegative | 74 (72) | 29 (28) | ||
| Previous history of TB | ||||
| No previous therapy | 52 (80) | 13 (20) | 2.53 (0.89 to 7.22) | 0.05 |
| Previously treated | 19 (61) | 12 (39) | ||
| Drug resistance | ||||
| Drug resistanceb | 22 (71) | 6 (29) | 1.56 (0.51 to 4.97) | NS |
| Susceptible to all drugs | 54 (70) | 23 (30) | ||
| Radiologic findings | ||||
| Extensive cavitary | 12 (76) | 5 (24) | 1.6 (0.33 to 11.22) | NS |
| Limited cavitary | 6 (60) | 4 (40) | ||
| Sputum smear positive | ||||
| 1–10 AFB/10–100 fields | 30 (73) | 11 (27) | 0.96 (0.34 to 2.70) | NS |
| >1 AFB per field | 37 (74) | 13 (26) | ||
aOR, odds ratio; CI, confidence interval; TB, tuberculosis; NS, not statistically significant; UD, undefined; AFB, acid-fast bacilli. bResistance to one or more drugs.