Table 2. 1-EBIO has little effect on arterial blood pressure (BP) or blood gases.
|
Vehicle |
1-EBIO |
|
|---|---|---|
| Average s.e.m. | Average s.e.m. | |
| Baseline (10 minutes before induction of CA) | ||
| BP | 74.9±2.2 | 74.0±1.4 |
| pH | 7.303±0.014 | 7.279±0.028 |
| PaCO2 | 44.0±3.0 | 43.6±2.0 |
| PaO2 | 148.1±9.0 | 138.2±7.3 |
| HCO3– | 21.1±0.9 | 20.1±1.4 |
| BE | –5.1±0.6 | –6.4±1.6 |
| Na | 150.7±1.5 | 148.3±1.7 |
| K | 5.2±0.2 | 5.2±0.1 |
| Cl | 115.4±1.7 | 111.7±1.7 |
| Glu | 206.6±15.5 | 255.0±11.9 |
| Lac | 3.9±0.3 | 3.6±0.6 |
| Recovery (30 minutes after recovery of spontaneous circulation) | ||
| BP | 82.1±4.8 | 83.8±1.4 |
| pH | 7.001±0.042966 | 7.0153±0.025 |
| PaCO2 | 56.0±3.3 | 48.6±1.5 |
| PaO2 | 306.2±15.5 | 291.2±1.1 |
| HCO3− | 13.7±1.3 | 12.2±0.8 |
| BE | −17.9±1.9 | −18.8±1.1 |
| Na | 150.1±1.3 | 149.0±1.4 |
| K | 6.3±0.4 | 5.7±0.4 |
| Cl | 122.0±1.6 | 118.0±1.2 |
| Glu | 271.5±25.3 | 324.3±48.2 |
| Lac | 4.9±0.9 | 4.2±0.9 |
CA, cardiac arrest; 1-EBIO, 1-ethyl-benzimidazolinone.